Cincinnati Masters 2022: Stefanos Tsitsipas vs. John Isner Tennis Pick and Prediction

TennisSection previews the 2022 Cincinnati Open as Stefanos Tsitsipas takes on John Isner in the quarterfinals on Friday, August 19th, 2022.

Will Stefanos Tsitsipas get the win? Will John Isner pull off the upset? This will be a fascinating one, where we have one of the world’s best taking on a dangerous American. Who will triumph and move on to the semifinals at the 2022 Cincinnati Open?

Stefanos Tsitsipas got a great win over Diego Schwartzman, taking him down 6-3 6-3, as he looks ahead to John Isner, he knows it’s going to be a tough battle. Although Tsitsipas is playing quite well and he has a good record against the giant, Isner is playing at home and his serve may trouble the Greek who hasn’t been in his best form as of lately. It’s gonna be a tight one as the two clash for an all-important spot in the last 4 at the 2022 Cincinnati Open.

John Isner took down Sebastian Korda in 3 sets, 7-6 1-6 7-6, it was a big win for him as he’s been struggling lately, but it’s only going to get harder as he comes up against the fourth seed in Stefanos Tsitsipas. If he wants to win, he’s going to have to serve his very best. I don’t see him being able to break Tsitsipas, but if he can edge him out in the tiebreakers, it’s very likely that he can make something happen at home here at the 2022 Cincinnati Open.

Stefanos Tsitsipas and John Isner have met six times before, with Stefanos Tsitsipas leading the head to head 4-2. The only wins Isner got were their first 2 meetings, with Tsitsipas winning the next 4, even one here in Cincinnati. Tsitsipas may be the favorite, but Isner will have a lot of motivation and I think he absolutely has what it takes to hold his own on serve, and I think he just may be able to pull this one off here at the 2022 Cincinnati Open.